Fullmetal Alchemist 2: Curse of the Crimson Elixir

A frightening phenomenon is sweeping the country; people in many regions are vanishing without a trace. In Resembool, Edward and Alphonse meet an enigmatic alchemist. It seems that he has some connection with both the disappearances and the strange creatures. Edward and Alphonse soon find themselves headed for the ruins of Siam-Sid, the capital city of Lebis, to discover the truth behind the monstrous creatures and the puzzling disappearances. (metacritic)