Re-Loaded

F.U.B. had his body destroyed at the end of the previous game, although his brain fled in an escape pod. Landing on a harsh desert world, Kee-Butt-5, his brain has been implanted into the body of a chiselled, bronzed young artist hermit named Manuel Auto, and then he murdered the loyal surgeons responsible for giving him a new body. Once again the group of blood-thirsty anti-heroes gather to bring him down once and for all and set off for Kee-Butt-5. (wiki)