The Binding of Isaac: Rebirth (2014)

When Isaac's mother starts hearing the voice of God demanding a sacrifice be made to prove her faith, Isaac escapes into the basement facing droves of deranged enemies, lost brothers and sisters, his fears, and eventually his mother.
Game Information
Genre: Action
Platforms: PS4, Xbox One, Windows, Switch, PS Vita, Wii U, Nintendo 3DS, iOS, Linux, macOS
Franchise: The Binding of Isaac
Expansions: The Binding of Isaac: Afterbirth +
The Binding of Isaac: Afterbirth
The Binding of Isaac: Repentance
Developer: Nicalis
Publisher: Nicalis